Safety and Toxicity of Nonoxynol-9 Gel As a Rectal Microbicide
Nonoxynol-9 (N-9) appears to be relatively safe for gay men who have anal sex to use. This drug was developed to prevent HIV infection. It is inserted into the vagina or rectum and can be used by women and gay men. Twenty-five HIV-negative and 10 HIV-positive gay men used N-9 gel or a placebo gel alternatively during anal sex. Rectal exams and rectal biopsies at 1, 2, 5, and 6 weeks showed no rectal ulcers as a result of the treatment. However, 89% of the men had abnormal tissue changes after using N-9 compared to 69% after using the placebo gel.
Publication Name: Sexually Transmitted Diseases
Security on the Internet: is your system vulnerable?
Ten basic steps performed routinely can help prevent unwanted access and contamination of an organization's Internet system. These steps include developing unusual and routinely changed passwords, installing current editions of all software including antivirus software, and monitoring system directories for unknown programs. Other safeguards include monitoring physical access, system access, and data locations. A buffer computer restricting Internet access can also protect against abuse.
Publication Name: Nursing Management
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