Structured treatment interruptions in primary HIV-1 infection

Article Abstract:

A study is conducted to examine whether structured treatment interruptions (STIs) can induce anti-HIV immune response and control HIV replication following discontinuation of highly active antiretroviral therapy (HAART) in patients with primary HIV infection. The results failed to establish that a significant proportion of patients with primary HIV infection could maintain suppression of viremia after a sequence of HAART/STIs followed by HAART discontinuation.

Author: Raffi, Francois, Burgard, Marianne, Chaix, Marie-Laure, Rouzioux, Christine, Molina, Jean-Michel, Livrozet, Jean-Michel, Aboulker, Jean-Pierre, Hoen, Bruno, Lacabaratz, Christine, Charreau, Isabella, Venet, Alain, Fournier, Isabella
United States, HIV infection, HIV infections, Immune response, Highly active antiretroviral therapy

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CCR2B-64I chemokine receptor allele and mother-to-child HIV-1 transmission or disease progression in children

Article Abstract:

Having the CCR2B-64I receptor does not appear to protect children from HIV infection. In a study of 745 children born to HIV-infected women, this receptor was just as likely to occur in HIV-infected children as in non-infected children.

Author: Burgard, Marianne, Rouzioux, Christine, Mayaux, Marie-Jeanne, Blanche, Stephane, Delfraissy, Jean Francois, Misrahi, Micheline, Teglas, Jean Paul, N'Go, Nicole
Risk factors, Cell receptors

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Predictive factors of virologic success in HIV-1-infected children treated with lopinavir/ritonavir

Article Abstract:

The study was aimed to analyze and determine genotypic and pharmacologic predictive factors of virologic success. A prospective genotypic resistance analysis was also performed in patients who experienced virologic failure.

Author: Delaugerre, Constance, Chaix, Marie-Laure, Rouzioux, Christine, Blanche, Stephane, Veber, Florence, Treluyer, Jean-Marc, Jullien, Vincent, Teglas, Jean-Paul, Vaz, Paula
Ritonavir, Genotype, Genotypes, Dosage and administration

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Subjects list: Health aspects, Care and treatment, Research, HIV infection in children, Pediatric HIV infections
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