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Potentiation of Vitamin K Antagonists by High-Dose Intravenous Methylprednisolone

Article Abstract:

Patients who are taking anticoagulants and methylprednisolone should be monitored very closely. In a study of 10 patients taking both drugs and 5 taking methylprednisolone alone, those taking both drugs had prolonged blood clotting times. This means that it took longer for their blood to clot.

Health aspects, Analysis, Anticoagulants (Medicine), Anticoagulants, Drug interactions, Methylprednisolone

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Systemic vasculitis with bilateral perirenal haemorrhage in chronic myelomonocytic leukaemia

Article Abstract:

Researchers describe two cases of patients with chronic myelomonocytic leukemia who developed systemic vasculitis. Vasculitis is an inflammation of blood vessels. This is the first known description of the association between these two diseases.

Causes of, Vasculitis, Chronic myeloid leukemia

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Parvovirus B19 infection, hepatitis C virus infection, and mixed cryoglobulinaemia

Article Abstract:

Parvovirus B19 does not appear to be cause of mixed cryoglobulinemia (MC). MC is a disorder characterized by an inflammation of small and medium blood vessels and excessive levels of antibodies in the blood. Researchers tested 28 patients with MC and 36 patients with hepatitis C for antibodies against parvovirus B19. Half of the hepatitis C patients also had MC. Seventy-two percent of the 64 patients had antibodies against parvovirus B19, which is close to the value (60%) in the general population. Patients without MC were just as likely to have antibodies against the virus as those with MC.

Testing, Risk factors, Parvoviruses, Cryoglobulinemia

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