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The TIMI Risk Score for Unstable Angina/Non--ST Elevation MI: A Method for Prognostication and Therapeutic Decision Making

Article Abstract:

Seven characteristics can predict the risk of heart attack or death in patients with chest pain. They are: age 65 years or older, at least 3 risk factors for coronary artery disease, coronary artery blockage of 50% or more, ST-segment changes on an ECG, at least 2 episodes of chest pain in the past 24 hours, use of aspirin in the past seven days, and elevated serum cardiac markers.

Author: Corbalan, Ramon, Antman, Elliott M., Cohen, Marc, Bernink, Peter J. L. M., McCabe, Carolyn H., Horacek, Thomas, Papuchis, Gary, Mautner, Branco, Radley, David, Braunwald, Eugene
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
Methods, Risk factors, Unstable angina, Health risk assessment

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Application of the TIMI Risk Score for ST-Elevation MI in the National Registry of Myocardial Infarction 3

Article Abstract:

The TIMI risk score can be used to estimate the prognosis of heart attack patients, according to a study of 84,029 patients. This score is a summary of eight characteristics, including age, medical history, weight, blood pressure, heart rate, the nature of the heart attack, and whether the patient received reperfusion therapy.

Author: Antman, Elliott M., Barron, Hal V., Cannon, Christopher P., McCabe, Carolyn H., Braunwald, Eugene, Giugliano, Robert P., Morrow, David A., Parsons, Lori, de Lemos, James A.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2001
Research

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Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes

Article Abstract:

The blood serum marker troponin I may serve to identify an increased risk of death in patients with unstable angina or a heart attack. Troponin I, a part of the troponin regulatory mechanism, is not detected in the blood of healthy people and is highly specific for heart tissue. By day 42 of a study of cardiac patients, the 573 patients with troponin I levels above 0.4 nanograms (ng) per milliliter had a mortality rate almost four times that of 831 patients with lower troponin I concentrations. Risk of death increased significantly with each 1.0 ng increase of troponin I, even after adjustment for patient characteristics, such as electrocardiographic results and age.

Author: Antman, Elliott M., Cannon, Christopher P., McCabe, Carolyn H., Braunwald, Eugene, Thompson, Bruce, Fischer, George A., Thompson, Christopher, Schactman, Mark, Tanasijevic, Milenko J., Fung, Anthony Y., Wybenga, Donald
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1996
Patient outcomes, Mortality, Measurement, Physiological aspects, Coronary heart disease, Carrier proteins, Transport proteins, Muscle proteins, Cardiac patients, Biological response modifiers

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Subjects list: Evaluation, Prognosis, Heart attack, Health status indicators
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