Umbilical arteritis and phlebitis mark different stages of the fetal inflammatory response

Article Abstract:

Fetuses with umbilical arteritis have higher cytokine responses and a worse prognosis than those who don't have umbilical arteritis. Umbilical arteritis is an inflammation of the umbilical arteries.

Fetal diseases, Arteritis

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The frequency and clinical significance of intra-amniotic inflammation in patients with a positive cervical fetal fibronectin

Article Abstract:

Pregnant women who have fetal fibronectin in cervical fluid and evidence of uterine inflammation have a very high risk of delivering prematurely. In a study of 58 pregnant women with a positive test for fetal fibronectin, uterine inflammation was diagnosed based on increased amounts of interleukin-6 in amniotic fluid.

Risk factors, Fibronectins, Premature birth, Inflammation, Uterus

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High expression of tumor necrosis factor-alpha and interleukin-6 in periventricular leukomalacia

Article Abstract:

Two cytokines, interleukin-6 and tumor necrosis factor-alpha, appear to contribute to the development of a brain lesion frequently associated with cerebral palsy called periventricular leukomalacia. Brain samples from 17 newborns who died with periventricular leukomalacia and 17 matched newborns who died without the lesions were analyzed for the presence of various cytokines. Interleukin-6 was present in 71% of the samples with lesions but only 6% of those without the lesions. Tumor necrosis factor-alpha was present in 82% of the samples with lesions but only 18% of those without the lesions.

Measurement, Physiological aspects, Tumor necrosis factor, Brain diseases, Interleukin-6

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