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The impact of gene therapy on dentistry

Article Abstract:

Applications of gene therapy to dental and oral problems illustrate the potential impact of this technology on dentistry. Gene therapy is the transfer of a foreign gene into a cell. University of Texas researchers are using gene therapy to treat oral cancer and precancerous lesions. The transferred genes prohibit cancer cells from producing a protein necessary for tumor formation. Researchers at the State University of New York at Stony Brook are transferring foreign genes into a type of skin cell called a keratinocyte. The foreign gene produces protein products that are pharmaceutical agents. This approach may be used in the future to increase subnormal hormone secretion or to correct genetic skin disorders. Researchers at the National Institute of Dental Research in Maryland are using gene therapy to repair damaged salivary gland cells. In addition, gene transfer into salivary cells may stimulate the production of foreign protein products that may one day prevent oral fungal infection or plaque formation.

Gene therapy

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The impact of tissue engineering on dentistry

Article Abstract:

Tissue engineering will have a substantial impact on dentistry. Tissue engineering involves growing biological tissues in the laboratory, or giving patients drugs that stimulate tissue formation in the body. Skin, connective tissues, and even bone can be produced in this way. Dental applications include periodontal disease, bone grafts, cavities, and lost teeth. Gene therapy could be used to stimulate saliva production in patients with Sjogren's disease or those who have received radiation therapy for head and neck cancer. Drugs could be used to stimulate wound healing inside the mouth.

Health aspects, Artificial organs

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Practicing dentistry in the age of telemedicine

Article Abstract:

Telemedicine may revolutionize dental care for many patients, but several issues must be addressed and resolved. They include interstate licensure, jurisdiction and malpractice, and technological, security, and ethical issues. Telemedicine uses electronic communication to provide health care services over long distances.

Telemedicine

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