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Tiotropium (Spiriva) for COPD

Article Abstract:

The approval of a drug named Tiotropium bromide inhalation powder (Spiriva Handihaler-Boehringer Ingelheim) by the FDA is discussed. This long-acting inhaled anticholinergic drug for treatment of chronic obstructive pulmonary disease (COPD) improves lung function, reduces symptoms, improves quality of life and decreases the number of exacerbations with once-daily dosing.

Government regulation, Drugs, Licensing, certification and accreditation, Lung diseases, United States. Food and Drug Administration, Inhaled medication

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Prilosec, Nexium and Sterioisomers

Article Abstract:

Clinical testing reveals that drug sterioisomers of the old drugs differ from each other and from the racemic mixture of the two in their pharmacokinetics, activity and toxicity. Data indicate that the S-isomer levofloxacin is better than the racemic ofloxacin. The effectiveness as claimed by pharmaceutical manufacturers are not substantiated.

Analysis, Drug use, Stereoisomers

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Newer antihistamines; Esomeprazole (Nexium); Bivalirudin (Angiomax) for angioplasty

Article Abstract:

This newsletter introduces three new drugs for allergy, proton pump inhibitor drugs for GERD treatment, and bivalirudin for coronary angioplasty. The dosage , pharmacokinetics, clinical study findings, adverse side effects and cost are described for each of the above formulary.

Research, Complications and side effects, Therapeutics, Omeprazole, Angioplasty, Cetirizine, Loratadine, Lansoprazole, Rabeprazole, Rabeprazole sodium

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