Transcoronary transplantation of progenitor cells after myocardial infarction
Article Abstract:
A study investigates whether intracoronary infusion of progenitor cells into the infarct-related artery at least three months after myocardial infarction improves global and regional left ventricular function. Evidence suggests that intracoronary infusion of progenitor cells is safe and feasible in patients with healed myocardial infarction, and that transplantation of bone marrow (BMC) is associated with moderate but significant improvement in the left ventricular ejection fraction after three months.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2006
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Prognostic value of placental growth factor in patients with acute chest pain
Article Abstract:
Increased blood levels of a protein called placental growth factor may be a risk factor for heart attack in patients with chest pain from coronary artery disease, according to a study of 1,173 patients. Those with elevated placental growth factor were three times more likely to have a heart attack within 30 days than other patients. Placental growth factor may increase during inflammation.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2004
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Soluble CD40 ligand in acute coronary syndromes
Article Abstract:
Increased blood levels of soluble CD40 ligand in patients with coronary artery disease is a risk factor for heart attack and death, according to a study of 1,088 patients. This protein occurs on cells involved in blood clotting and is shed into the bloodstream when these cells are activated. It can cause inflammation in this state, which can worsen the patient's prognosis.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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