Prenatal zidovudine use and congenital anomalies in a Medicaid population

Article Abstract:

Zidovudine may increase the risk of birth defects in babies born to women who took the drug during pregnancy. In a study of 1,932 babies born to HIV-infected women who took the drug, the rate of birth defects was almost three times higher than in the general population.

Author: Newschaffer, Craig J., Cocroft, James, Anderson, Carol E., Hauck, Walter W., Turner, Barbara J.
Complications and side effects, Risk factors, Fetus, Birth defects, Zidovudine

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Association of provider and patient characteristics with HIV-infected women's antiretroviral therapy regimen

Article Abstract:

HIV-infected women are more likely to receive highly active antiretroviral therapy (HAART) is their doctors have experience treating HIV infection, if they are older than 25, and if they have more than a high school education. Drug addicts on methadone were also more likely to receive HAART than other drug users.

Author: Pomerantz, Roger J., Hauck, Walter W., Turner, Barbara J., Laine, Christine, Zhang, Daozhi, Cosler, Leon
Women, HIV infection in women

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Translating Clinical Trial Results into Practice: The Effect of an AIDS Clinical Trial on Prescribed Antiretroviral Therapy for HIV-Infected Pregnant Women

Article Abstract:

Efforts to disseminate research on AIDS prevention techniques substantially increased the use of antiretroviral therapy in HIV-infected pregnant women. Antiviral drugs during pregnancy and after delivery significantly reduce the transmission of HIV infection to children. Researchers compared the treatment of 2,607 pregnant women with HIV from 1993 to 1996. The odds of receiving antiviral drugs in late pregnancy increased 21% each month following the publication of AIDS prevention research in 1994. Women who received prenatal care, attended HIV-focused facilities or those participating in HIV research, or attending methadone clinics were most likely to receive appropriate drugs to prevent HIV infection of their children.

Author: Newschaffer, Craig J., Hauck, Walter W., Turner, Barbara J., Zhang, Daozhi, Fanning, Thomas
United States, Health aspects, Clinical trials, Disease transmission, Media coverage, Antiviral agents

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Subjects list: Drug therapy, HIV infections, Pregnancy, HIV infection in pregnancy
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