Update on primary HIV-1 resistance in Argentina: Emergence of mutations conferring high-level resistance to nonnucleoside reverse transcriptase inhibitors in drug-naive patients
Article Abstract:
A survey report on 52 drug-naive HIV-1-infected subjects from Buenos Aires City and province and 3 other regions in Argentina is presented. Results reveal a need for sentinel resistance surveillances calling for an update in the present resistance testing guidelines in Argentina.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
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Development and significance of the HIV-1 reverse transcriptase M184V mutation during combination therapy with lamivudine, zidovudine, and protease inhibitors
Article Abstract:
The development of a gene mutation that makes HIV resistant to lamivudine may make it more sensitive to zidovudine. In a study of 56 HIV patients, half of those treated with zidovudine developed resistance to lamivudine compared to 19% who were not treated with zidovudine.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 1999
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Nonnucleoside reverse transcriptase inhibitor resistance
Article Abstract:
HIV can develop resistance to non-nucleoside reverse transcriptase inhibitors very quickly. This class of drug includes nevirapine, delavirdine, and efavirenz. Doctors must keep this in mind when using these drugs to treat HIV infection.
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
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