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Update on primary HIV-1 resistance in Argentina: Emergence of mutations conferring high-level resistance to nonnucleoside reverse transcriptase inhibitors in drug-naive patients

Article Abstract:

A survey report on 52 drug-naive HIV-1-infected subjects from Buenos Aires City and province and 3 other regions in Argentina is presented. Results reveal a need for sentinel resistance surveillances calling for an update in the present resistance testing guidelines in Argentina.

Author: Petroni, Alejandro, Rotryng, Flavio, Deluchi, Gabriel, Pryluka, Daniel, Bortolozzi, Raul, Lopardo, Gustavo, Bouzas, Maria Belen, Zapiola, Ines, Garone, Daniela, Rodriguez, Claudia, Chiocconi, Eduardo, Lazaro, Maria Esther, Murano, Fernando, Maranzana, Aldo, Oliva, Stella Maris, Aparicio, Marta, Beltran, Marcelo, Benetucci, Jorge A.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2006
Argentina, Reports, HIV infection, HIV infections, Drug resistance

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Development and significance of the HIV-1 reverse transcriptase M184V mutation during combination therapy with lamivudine, zidovudine, and protease inhibitors

Article Abstract:

The development of a gene mutation that makes HIV resistant to lamivudine may make it more sensitive to zidovudine. In a study of 56 HIV patients, half of those treated with zidovudine developed resistance to lamivudine compared to 19% who were not treated with zidovudine.

Author: Zazzi, Maurizio, Catucci, Marinunzia, Venturi, Giulietta, Romano, Laura, Riccio, Maria Letizia, De Milito, Angelo, Valensin, Pier E.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 1999
Protease inhibitors, Zidovudine, Lamivudine

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Nonnucleoside reverse transcriptase inhibitor resistance

Article Abstract:

HIV can develop resistance to non-nucleoside reverse transcriptase inhibitors very quickly. This class of drug includes nevirapine, delavirdine, and efavirenz. Doctors must keep this in mind when using these drugs to treat HIV infection.

Author: Deeks, Steven G.
Publisher: Lippincott Williams & Wilkins, WK Health
Publication Name: Journal of Acquired Immune Deficiency Syndromes (1999)
Subject: Health
ISSN: 1525-4135
Year: 2001
HIV (Viruses), HIV

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Subjects list: Health aspects, Research, Drug resistance in microorganisms, Microbial drug resistance
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