Ethical challenges of HIV clinical trials in developing countries
Article Abstract:
For bioethicists, challenges are presented by HIV clinical trials in less-developed countries. The same standards should prevail, no matter where the trials take place and the interests f the research subjects should be primary. Clinical trials are profitable for pharmaceutical companies and for clinical researchers. They want to do them as quickly as possible with as few obstacles as possible and that often means going to developing countries. Medical pluralism would suggest that non-Western medical systems could have a role in managing HIV infection and that that should be explored. Non-market forces might facilitate treatment. David B. Resnik has not identified all of the scientific/ethical issues.
Publication Name: Bioethics
Subject: Philosophy and religion
ISSN: 0269-9702
Year: 1998
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Unethical perinatal HIV transmission trials establish bad precedent
Article Abstract:
Clinical trials that took place in developing countries for testing zidovudine effectiveness in cutting the perinatal HIV transmission rate have been defended by David B. Resnik. The trials are unethical and establish bad precedent. It would not even be defensible to carry out tests on using levels of the drug lower than the AIDS Clinical Trial Group (ACTG) 076 levels. The placebo control groups are not necessary, based on the judgement of a number of eminent scientists who conduct such trials.
Publication Name: Bioethics
Subject: Philosophy and religion
ISSN: 0269-9702
Year: 1998
User Contributions:
Comment about this article or add new information about this topic: