Mechanisms of protein assembly: Lessons from minimalist models

Article Abstract:

Many cellular functions rely on interactions among proteins and between proteins and nucleic acids. The power of native topology-based models to study the mechanisms of biological binding is discussed where the models propose the importance of flexibility, and also the electrostatic and water-mediated interactions, for the assembly of some proteins.

United States, Usage, Protein binding, Nuclear magnetic resonance, Transition state (Chemistry)

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Enamides and enecarbamates as nucleophiles in stereoselective C-C and C-N bond-forming reactions

Article Abstract:

The article discusses the benefits of using several enamides and enecarbamates as the nucleophiles in the several stereoselective reactions that lead to the formation of C-C and C-N bonds. These compounds are easily available and hence are even being used in the Lewis acid-catalyzed reactions.

Nuclear magnetic resonance spectroscopy, Spectra, Amides, Structure, Chemical properties, Lewis structures

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