Natural selection at work on the surface of virus-infected cells
Article Abstract:
Recognition of major histocompatibility complex class 1 (MHC-1) molecules in a cell by cytotoxic T lymphocytes (CTLs) is important in the immune response to viral infection. A natural selection process is at work in the ratios of T cells created that do or do not kill target cells.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1993
Research, Virus diseases, Cell-mediated cytotoxicity, Cell mediated cytotoxicity, Major histocompatibility complex, Immune response
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1993
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TH2 downregulation of macrophage HIV-1 replication
Article Abstract:
Research indicates a dichotomy in the results that TH2-type cytokines produce in macrophages affected by HIV. Variables that affect preferential replication of HIV-1 are discussed.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1995
Physiological aspects, HIV infection, HIV infections, Cytokines
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1995
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