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Innovative immunity: a biological trick offers a promise for making vaccines from RNA

Article Abstract:

Christian W. Mandl and colleagues have developed a method for constructing a vaccine which protected mice from tick-borne encephalitis. Mandl used RNA corresponding to an almost complete genome of the virus causing the disease. The RNA was fired into the skin of the mice by a gene gun.

Author: Beardsley, Tim
Publisher: Scientific American, Inc.
Publication Name: Scientific American
Subject: Science and technology
ISSN: 0036-8733
Year: 1999
Vaccines, RNA

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Gene therapy setback: a tragic death clouds the future of an innovative treatment method

Article Abstract:

The death of gene therapy patient Jesse Gelsinger in a University of Pennsylvania clinical trial uncovered numerous troubling methodology breaches on the part of the researchers involved in the trial. The case points to the need for more strict adherence to guidelines.

Author: Beardsley, Tim
Publisher: Scientific American, Inc.
Publication Name: Scientific American
Subject: Science and technology
ISSN: 0036-8733
Year: 2000
Health aspects, Care and treatment, Liver diseases, Gene therapy, Human experimentation in medicine, Human medical experimentation, Gelsinger, Jesse, Pennsylvania, University of. Institute for Human Gene Therapy

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Death by analysis

Article Abstract:

Environmentalists charge that several GOP-sponsored bills currently pending in Congress would make it impossible or extremely difficult to administer existing environmental laws. In addition, these bills require the EPA to spend more money on cost-benefit studies.

Author: Beardsley, Tim
Publisher: Scientific American, Inc.
Publication Name: Scientific American
Subject: Science and technology
ISSN: 0036-8733
Year: 1995
Laws, regulations and rules, United States. Environmental Protection Agency, Environmental policy, Republican Party (United States)

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