Simultaneous determination of positive and negative counterions using a hydrophilic interaction chromatography method

Article Abstract:

A study was conducted to develop a high performance liquid chromatography method that can simultaneously retain and separate cations and anions in a single chromatographic analysis for quantification in pharmaceutical products. A zwitterionic stationary phase working in the hydrophilic interaction chromatography (HILIC) mode was analyzed. Results of the experiments show that a large number of cations and anions can be separated by evaporative light scattering detection.

Author: Risley, Donald S., Pack, Brian W.
Usage, Liquid chromatography

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Modern techniques for the extraction of solid materials - an update

Article Abstract:

Methods for the extraction of solid materials are discussed. Soxhlet extraction, which is the most widely-used technique for pretreatment of solid samples, provides good analyte recovery but uses huge amounts of solvent. The processes involved in Soxhlet extraction, as well as details of other extraction methods, are also presented.

Author: Majors, Ronald E.
Discovery and exploration, Solids, Extraction (Chemistry)

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Subjects list: Methods, United States
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