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Will Dolly send in the clones? The first mammalian clone, produced from an adult sheep, took the world by storm, but leaves a rash of unanswered scientific questions in her wake

Article Abstract:

The cloning a sheep from an adult holds much promise for medicine and livestock, but little is understood about the process. Ian Wilmut and Keith Campbell were able to clone adult DNA only on the 227th try. DNA is normally only totipotent if taken from the first four embryonic cells.

Author: Williams, Nigel, Pennisi, Elizabeth
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997

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After Dolly, a pharming frenzy

Article Abstract:

The cloning technologies that spawned Dolly and two Holstein calves are giving rise to efforts to create transgenic livestock that will serve as living laboratories. But the technology is still very inefficient and needs much improvement.

Author: Pennisi, Elizabeth
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1998
Innovations, Genetically modified animals

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The lamb that roared

Article Abstract:

The cloning of a lamb from a single cell of a six-year-old ewe was a stunning achievement that may have applications in many areas of research. However, the technology ignited a controversy about the ethical implications of cloning.

Author: Pennisi, Elizabeth
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997
Cover Story, Genetic aspects, Ethical aspects, Sheep, Reproductive technology

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Subjects list: Research, Cloning
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