Nocturnal polyuria in older people: pathophysiology and clinical implications

Article Abstract:

Nocturnal polyuria in older people has been studied relative to pathophysiology and clinical implications. Alzheimer's disease adds to the risk. Treatment with the antidiuretic hormone analog desmopressin can bring lower nocturnal urine production and improvement in symptoms. Several factors contribute to changes in the circadian rhythm of water excretion with aging.

Health aspects, Urinary incontinence, Alzheimer's disease, Urinary organs, Urine, Desmopressin, Urinary tract

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Cellular ionic alterations with age: relation to hypertension and diabetes

Article Abstract:

A cross-sectional study has been carried out in a university hospital in New York to evaluate cellular divalent cations in normal subjects at different ages and their relationship to ion levels in essential hypertension and diabetes. It was found that aging is associated with onset of altered cytosolic free calcium (Cai) and magnesium (Mgi) levels, indistinguishable from those observed in hypertension and diabetes, independent of age. The ionic changes may be clinically significant and may underlie predisposition of older subjects to cardiovascular and metabolic diseases. NMR techniques were used for intracellular measurement.

Research, Hypertension, Demographic aspects, Diabetes, Diabetes mellitus, Cytochemistry, Calcium in the body, Calcium (Nutrient), Ions, Magnesium in the body, Magnesium (Nutrient)

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Hyponatremia and Arginine Vasopressin Dysregulation: mechanisms, clinical consequences, and management

Article Abstract:

An analysis on clinical and physiological factors affecting Arginine Vasopressin Dysregulation (AVP) that puts the older individual at risk for advancement of hyponatremia, clinical assessment, outcomes of hyponatremia, present priniciples of management, and further treatment with aquaretic drugs, is discussed.

Risk factors, Dosage and administration, Hyponatremia, Vasopressin, Vasopressins

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