Abstracts » Zoology and wildlife conservation

A new escape and evasion tactic

Article Abstract:

Plasmodium, the mosquito-borne parasites responsible for malaria, have developed a range of molecular strategies to avoid a host blockade against invasion. New research in this area has identified an unusual and very interesting method of clonal phenotypic variation used by the Plasmodium species P. yoelii to avoid blockade by its host, a small African rodent. This molecular variation takes place during the development of the invasive merozoite parasite form. Researchers analyzed p235 transcripts in individual parasites, and now believe that a single p235 gene is transcribed in each nucleus that is replicated during schizogony.

Plasmodium, Plasmodium (Protozoa)

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A rhoptry-protein-associated mechanism of clonal phenotypic variation in rodent malaria

Article Abstract:

The number of Py235 genes transcribed in the rodent malaria agent P. yoelii yoelii, in which a multigene family codes for merozoite rhoptry proteins of relative molecular mass 235,000, correlates directly with the number of nuclei present in the parasite. The pattern of transcription identified in this research suggests a mechanism by which the parasite can adapt efficiently to changes in the host environment. The ability of the parasite to maintain the infection, and thereby boost its potential for transmission, is optimized by ensuring that a single schizont produces merozoites with a distinct specificity.

Rodents

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The billion-dollar malaria moment

Article Abstract:

The strategies, interventions and the funding techniques that are being adopted in Africa to reduce the number of malaria cases and deaths in the country are analyzed. The practice of sleeping under bed nets, spraying houses with pesticides, special treatment for pregnant women and proper treatment of the sick people are found to be extremely important to overcome the problem.

Africa, Care and treatment

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