A new redox-cofactor vitamin for mammals
Article Abstract:
A pyrroloquinoline quinone-dependent dehydrogenase enzyme is identified, that is crucial for the degradation of the amino acid lysine, and the same is tested in mice. Pyrroloquinoline quinone acts as a mammalian redox cofactor in the experiment conducted, and therefore can be classified as a new B vitamin.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genome instability
Article Abstract:
Stromelysin-1/matrix metalloproteinase -3 (MMP-3), a stromal enzyme upregulated in many breast tumors is investigated. The findings identify a component of the breast tumor microenvironment that alters cellular structure in culture and tissue structure in vivo leading to malignant transformation.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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Aid for AID
Article Abstract:
The protein that can assist in activation-induced deaminase enzyme (AID) induced antibody diversification is studied. The findings suggest that the somatic hypermutation is supported by the B-cell-specific interaction between RPA and phosphorylated AID.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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