A new redox-cofactor vitamin for mammals

Article Abstract:

A pyrroloquinoline quinone-dependent dehydrogenase enzyme is identified, that is crucial for the degradation of the amino acid lysine, and the same is tested in mice. Pyrroloquinoline quinone acts as a mammalian redox cofactor in the experiment conducted, and therefore can be classified as a new B vitamin.

Care and treatment, Identification and classification, Oxidoreductases, Mammals

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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genome instability

Article Abstract:

Stromelysin-1/matrix metalloproteinase -3 (MMP-3), a stromal enzyme upregulated in many breast tumors is investigated. The findings identify a component of the breast tumor microenvironment that alters cellular structure in culture and tissue structure in vivo leading to malignant transformation.

All Other Basic Organic Chemical Manufacturing, Enzymes for Food Processing, Metalloproteins, Breast tumors, Breast tumours

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Aid for AID

Article Abstract:

The protein that can assist in activation-induced deaminase enzyme (AID) induced antibody diversification is studied. The findings suggest that the somatic hypermutation is supported by the B-cell-specific interaction between RPA and phosphorylated AID.

Lymphocytic leukemia

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