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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

Article Abstract:

The potential of AMP-activated protein kinase(AMPK), that acts as a fuel gauge to monitor cellular energy in the hypothalamus, in the regulation of food intake, was studied. The results indicate that the AMOPK activity is inhibited, either in the arcade and paraventricular hypothalamus or in the multiple hypothalamic regions by different factors.

Author: Kahn, Barbara B., Birnbaum, Morris J., Lee, Ann, Minokoshi, Yasuhiko, Alquier, Thierry, Furukawa, Noboru, Kim, Yong-Bum, Xue, Bingzhong, Mu, James, Foufelle, Fabienne, Ferre, Pascal, Stuck, Bettina J.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Adenylic acid, Adenosine monophosphate

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Identification of nesfatin-1 as a satiety molecule in the hypothalamus

Article Abstract:

A study was conducted to show that nesfatin, corresponding to NEFA/nucleobindin2 (NUCB2), a secreted protein of unknown function, is expressed in the appetite-control hypothalamic nuclei in rats. Nesfatin-1 was identified as a satiety molecule that is associated with melanocortin signaling in the hypothalamus.

Author: Shimizu, Hiroyuki, Oh-l, Shinsuke, Satoh, Tetsurou, Okada, Shuichi, Adachi, Sachika, Inoue, Kinji, Eguchi, Hiroshi, Yamamoto, Masanori, Imaki, Toshihiro, Hashimoto, Koushi, Tsuchiya, Takafumi, Monden, Tsuyoshi, Horiguchi, Kazuhiko, Yamada, Masanobu, Mori, Masatomo
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
United Kingdom, Physiological aspects, Rats, Rattus, Satiation

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Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1 alpha transcription coactivator

Article Abstract:

The article describes a process wherein insulin, through the protein kinase, holds on to the lipid catabolism in the liver thereby stopping the growth of type 2 diabetes.

Author: Birnbaum, Morris J., Li, Xinghai, Monks, Bobby, Ge, Qingyuan
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
United States, Health aspects, Prevention, Type 2 diabetes, Properties, Catabolism

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Subjects list: Research, Protein kinases, Hypothalamus
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