Allosteric modulation of the presynaptic Ca(super 2+) sensor for vesicle fusion

Article Abstract:

An investigation on whether the potentiation of neuro-transmitter release by phorbol esters, which target presynaptic protein kinase C (PKC)/munc-13 signalling cascades, exerts a direct effect on the Ca(super 2+) -sensitivity of vesicle fusion is presented. The results revealed that phorbol esters potentiate transmitter release by increasing the apparent Ca(super 2+) -sensitivity of vesicle fusion.

United States, Science & research, Protein kinases, Neural transmission, Synaptic transmission, Phorbol esters

---

Direct modulation of synaptic vesicle priming by GABA (sub)B receptor activation at a glutamatergic synapse

Article Abstract:

The authors descuss the study of second messenger cascade involving G proteins. They demonstrate that G-protein-mediated signalling, including gamma-amino butyric acid subtype B receptors, causes synaptic vesicle recruitment retardation during the sustained activity and after the short-term depression.

Germany, All Other Basic Organic Chemical Manufacturing, Industrial Organic Chemicals, Butyric Acid, G proteins, Amino acids

---

Intracellular calcium dependence of transmitter release rates at a fast central synapse

Article Abstract:

Research is presented concerning the influence of neurotransmitter release and calcium-triggered fusion of synaptic vessels in the central nervous system's signalling ability.

Central nervous system, Letter to the Editor, Calcium, Calcium (Chemical element)

Similar abstracts:

• Abstracts: A possible docking and fusion particle for synaptic transmission. SNAP receptors implicated in vesicle targeting and fusion
• Abstracts: Experimental measurement of the photonic properties of icosahedral quasicrystals. Complete photonic bandgaps in 12-fold symmetric quasicrystals
• Abstracts: Polyamine-dependent facilitation of postsynaptic AMPA receptors counteracts paired-pulse depression. Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2
• Abstracts: Transgeneration memory of stress in plants. Pathogen-induced systematic plant signal triggers DNA rearrangements
• Abstracts: Kainate receptors are involved in synaptic plasticity. The synaptic activation of kainate receptors. Kainate receptors and synaptic plasticity

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.