Abstracts - faqs.org

Abstracts

Zoology and wildlife conservation

Search abstracts:
Abstracts » Zoology and wildlife conservation

Estimate of the genomic mutation rate deleterious to overall fitness in E. coli

Article Abstract:

The average effect of harmful mutations on fitness is 0.012 in Escherichia coli and the rate of harmful genomic mutations is almost 0.003 harmful mutations per haploid genome per generation. The effect of harmful mutations on E. coli fitness is similar to that in Drosophila melanogaster. The rate of harmful mutations is lower in E. coli due to a smaller genome size and fewer cell divisions/generation. Mean fitness decreases linearly with time as harmful mutations accumulate in different cell lines. The difference in fitness between lines containing different mutations increases with time.

Author: Lynch, Michael, Kibota, Travis T.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1996
Microbial mutation

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


A secreted protein kinase of Yersinia pseudotuberculosis is an indispensable virulence determinant

Article Abstract:

The pathogenic species of Yersinia enterobacteria all have a virulence plasmid which encodes a secreted protein kinase (YpkA) which may block phagocytosis by interference with signal transduction pathways in the target cells. Two mutants of the gene responsible for YpkA were studied and found not to produce the kinase activity. YkpA was also found to autophosphorylate. YpkA exhibits high homology with eukaryotic counterparts suggesting the hypothesis that the genes encoding it were recruited through horizontal gene transfer from a eukaryotic source.

Author: Galyov, Edouard E., Hakansson, Sebastian, Forsberg, Ake, Wolf-Watz, Hans
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1993
Protein kinases, Yersinia infections

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Parallel evolution of virulence in pathogenic Escherichia coli

Article Abstract:

Research is presented concerning the the evolution of pathogenic strains of the bacteria Esherichi coli. Phylogenitic analysis has revealed the parallel evolution of Shiga toxins, intestinal adhesion and plasmid-borne haemolysin.

Author: Reid, Sean D., Herbelin, Corinne J., Bumbaugh, Alyssa C., Selander, Robert K., Whittam, Thomas S.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
Evolution (Biology), Evolution, Letter to the Editor, Pathogenic microorganisms

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research, Genetic aspects, Escherichia coli, Virulence (Microbiology)
Similar abstracts:
  • Abstracts: Optimality, mutation and the evolution of ageing. Ageing, fitness and neurocognitive function. New approaches to old age: To truly understand ageing, we must look beyond the diseases of old age
  • Abstracts: You don't own me. From civil rights to animal rights: an evolution. A new order in the court
  • Abstracts: Dynamic organization of motor control within the olivocerebellar system. Genetic and epigenetic mechanisms contribute to motor neuron pathfinding
  • Abstracts: Complementary endeavours. Towards a resolution of the lek paradox. Distinct beta-catenins mediate adhesion and signalling functions in C. elegans
  • Abstracts: Locating global minima in optimization problems by a random-cost approach. Inspiration for optimization from social insect behavior
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2023 Advameg, Inc.