Global methylation in eutherian hybrids
Article Abstract:
A proposal by O'Neil et al that epigenetic processes help drive karyotypic evolution in marsupials disagree with the findings of a new study of three hybrids of placental mammals. The study of interspecific hybrids of Equidea (Perossodactyla), Muridae (Rodentia) and Camelidae (Artiodacytla) finds no evidence of changes in genome-wide methylation when compared with parental animals. It is suggested that the basic mechanisms of genome evolution may be different in marsupials and placental animals.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
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Demethylation of the zygotic paternal genome
Article Abstract:
Global methylation of paternal and maternal genomes in mouse pre-implantation embryos was analyzed using immunofluorescence against 5-methyl-cytosine (MeC). Paternal and maternal chromosomes stained equally intensely with anti-MeC antibody at three hours and six hours. This indicates the rapid de novo methylation of egg chromatin just after fertilization. Paternal pronnuclei were de-condensed and larger than the maternal pronuclei after eight hours.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen
Article Abstract:
The sequencing of the genome of pseudomonas aeruginosa, a bacterium, is reported.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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