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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium

Article Abstract:

The bone marrow serves as a reservoir for cardiac precursor cells is suggested by the adult bone marrow (BM) in the process of myocardial replication and regeneration. The reaction of the transformation of the cells from the transgenic mice expressing green fluorescent protein (GFT) to the ischaemic myocardium of wild-type mice is examined.

Author: Weissman, Irving, Balsam, Leora B., Wagers, Amy J., Christensen, Julie L., Kofidis, Theo, Robbins, Robert C.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Bone marrow, Animal experimentation

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Regulation of oxidation stress by ATM is required for self-renewal haematopoietic stem cells

Article Abstract:

The ATM has an essential function in the reconstitute capacity of haematopoietic stem cells (HSCs) but is not as important for the proliferation or differentiation of progenitors, in a telomere-independent manner. These results show that the self-renewal capacity of HSCs depends on ATM-mediated inhibition of oxidative stress.

Author: Mak, Tak W., Suda, Toshio, Keisuke Ito, HIrao, Atsushi, Arai, Fumio, Matsuoka, Sahoko, Sakurada, Kazuhiro, Hamaguchi, Isao, Nomiyama, Kana, Hosokawa, Kentaro, Takubo, Keiyo, Nakagata, Naomi, Ikeda, Yasuo
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Telomeres, Ataxia telangiectasia

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Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts

Article Abstract:

The trandifferentiation of the haematopoietic stem cells into unexpected phenotypes are suggested. Various clinical trials indicate that haematopoietic stem cells do not readily acquire a cardiac phenotype in myocardial infracts.

Author: Williams, David A., Murray, Charles E., Soonpaa, Mark H., Reinnecke, Hans, Nakajima, Hidehiro, Nakajima, Hisako O., Rubart, Michael, Pasumarthi, Kishore B.S., Virag, Jitka Ismail, Bartelmez, Stephen H., Poppa, Veronica, Bradford, Gillian, Dowell, Joshua, Field, Loren J.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Clinical trials, Heart attack

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Subjects list: Research, Stem cells
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