Abstracts » Zoology and wildlife conservation

Inside an intron invasion

Article Abstract:

Direct insertion of group II intron RNA, one of the four types of intervening sequences located between the protein-coding sequences of eukaryotic genes, into double-stranded DNA is possible. Group I and II introns catalyze reverse splicing into other RNAs. The insertion of intronic RNA into foreign RNAs followed by a reverse transcription to a DNA copy and integration into a genome may lead to intron migration.

Observations, Insertion elements, DNA, DNA insertion elements

---

Group II intron splicing in vivo by first-step hydrolysis

Article Abstract:

Group I, II and spliceosomal introns splice by sequential transesterification reactions. It is shown that the group II intron first-step hydrolysis reaction occurs in vivo instead of transesterifiction in the mitochondria of yeast strains having branch-site mutations, which block branching, but still allow accurate splicing.

Hydrolysis

---

A tertiary interaction that links active-site domains to the 5' splice site of a group II intron

Article Abstract:

A range of tertiary interactions are shown to link catalytically essential areas of domain 5 and domain 1.

Some parts © 2013 Advameg, Inc.