MISSION(super TM) shRNA library: Next generation RNA interference
Article Abstract:
Sigma-Aldrich assist the development, manufacturing and global distribution of The RNA interference Consortium's human and mouse lentiviral vector-based shRNA libraries (MISSION(super TM) shRNA) and it is committed to providing unmatched infrastructure and service for RNA interference research needs. Approximately 50,000 clones targeting 7,100 human and 2,900 mouse genes are available and the libraries include a broad range of gene families, functional classes, and druggable targets.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
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RNAi-mediated gene silencing in non-human primates
Article Abstract:
RNA interference (RNAi)-mediated silencing in response to systemic delivery of small interfering RNA in non-rodent species is presented. The results show clinically relevant RNAi-mediated gene silencing in non-human primates, supporting RNAi therapeutics as a potential new class of drugs.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
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RNA interference is an antiviral defense mechanism in Caenorhabditis elegans
Article Abstract:
The RNA interference is a sequence specific post-transcriptional gene silencing mechanism that is genetically defined in Caenorhabditis elegans. RNA is proposed to function as an adaptive antiviral immune mechanism.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
User Contributions:
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