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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein

Article Abstract:

Adenovirus E1A proteins stimulate cell cycling and viral transcription by interacting with critical cellular regulatory proteins. The E1A zinc-finger domain that is needed to activate transcription of viral early genes, is shown to bind to a host-cell multiprotein complex containing yeast Srb/Mediator protein homologues. The human Srb/Mediator complex responds to both the E1A zinc-finger and the herpes simplex virus VP15 activation domains, stimulating transcription in vitro.

Author: Lees, Emma, Boyer, Thomas G., Martin, Michelle E.D., Ricciardi, Robert P., Berks, Arnold J.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1999
Adenoviruses

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Activation of heat-shock response by an adenovirus is essential for virus replication

Article Abstract:

Research is presented concerning the activation of the cellular heat-shock responses which occur in proteins during the replicatation processes of viruses. The reasons for the responses are discussed.

Author: Glotzer, Jolanta B., Saltik, Mediyha, Chiocca, Susanna, Michou, Anne-Isabelle, Moseley, Pope, Cotten, Matt
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
Analysis, Viral research, Virus research, Letter to the Editor, Molecular microbiology

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Maternal effect of Hsf1 on reproductive success

Article Abstract:

The maternal effects of heat-shock factor-1 protein on reproductive success is examined.

Author: Christians, E., Davis, A.A., Thomas, S.D., Benjamin, I.J.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000

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Subjects list: Research, Viruses, Heat shock proteins
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