Movement of motor and cargo along cilia

Article Abstract:

Fluorescence microscopy has been used to visualize for the first time the intracellular transport of a motor and its cargo in vivo. An investigation of the anterograde movement of green fluorescent protein-labelled kinesin-II motors and intraflagellar transport (IFT) rafts within sensory cilia on chemosensory neurons in living Caenorhabditis elegans provides strong evidence that heterotrimeric kinesin-II is the motor protein that drives anterograde IFT. This work should make it possible to directly observe motor and cargo molecules taking part in IFT in a wide range of cilia and flagella.

Motor neurons, Microorganisms, Cell motility

---

Functional coordination of intraflagellar transport motors

Article Abstract:

Three genes whose protein products mediate the functional coordination of the intraflagellar transport (IFT) motors are identified by observing the movement of fluorescent IFT motors and IFT particles along the cilia of numerous ciliary mutants. IFT motors assemble and maintain cilia by transporting ciliary precursors, bound to protein complexes called IFT particles, from the base of the cilium to their site of incorporation at the distal tip.

United States, Science & research, Carrier proteins, Transport proteins, Caenorhabditis elegans, Structure, Cilia and ciliary motion, Cilia

---

Force-velocity relationships in kinesin-driven motility

Article Abstract:

Force-velocity curves obtained with the use of a centrifuge microscope show the maximal isometric force generated per kinesin in kinesin-driven motility is 0.12+ or -0.03 pN per molecule. A detailed explanation of the methodology used to arrive at this figure is included.

Physiological aspects, Microtubules, Kinesin

Similar abstracts:

• Abstracts: Locomotion and grooming in crickets: competition or time sharing? Grooming, competition and social rank among female primates: a meta-analysis
• Abstracts: Long-term potentiation and functional synapse induction in developing hippocampus. Per - no link to gap junctions
• Abstracts: US government and utilities revive California solar project. California looks to science partnerships...
• Abstracts: Gunning for goats: Olympic National Park is bent on ridding its mountains of aliens. GATTzilla the trade monster: why should we fear freer trade?
• Abstracts: Response of cells in monkey visual cortex during perceptual filling-in of an artificial scotoma. A neutral basis for visual search in inferior temporal cortex

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.