Myosin domain evolution and the primary divergence of eukaryotes

Article Abstract:

A survey of the myosin gene family indicates 37 myosin types with different combinations of protein domains and scattered taxonomic distribution. The diversity of myosin paralogues encoded by each eukaryote varies considerably, with Phytophthora ramorum having 25 myosin genes encoding 13 different types, and humans having 12, 6 of which are also present in Dictyostelium.

Author: Cavalier-Smith, Thomas, Richards, Thomas A.
Genetic research

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Atomic model of a myosin filament in the relaxed state

Article Abstract:

The structure of a phosphorylation-regulated striated muscle thick filament is analyzed using cryo-electron microscopy. The findings suggest that the 'interacting-head' structure is present in the filament and that it might underlie the relaxed state of thick filaments in both smooth and myosin-regulated striated muscles over a wide range of species.

Author: Egelman, Edward H., Woodhead, John L., Fa-Qing Zhaom, Craig, Roger, Alamo, Lorenzo, Padron, Raul
Analysis, Molecular structure

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The plasmodium protein network diverges from those of other eukaryotes

Article Abstract:

The degree of conservation between the Plasmodium protein network and those of model organisms is examined. Although 29 highly connected protein complexes specific to the network of the pathogen are found, very little conservation with complexes is observed in other organisms.

Author: Suthram, Silpa, Sittler, Taylor, Idekar, Trey
Plasmodium falciparum, Bacterial proteins

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Subjects list: Research, United States, Eukaryotes, Myosin
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