The bases for Cockayne syndrome
Article Abstract:
Cells in patients with Cockayne syndrome all fail to repair oxidation-induced damage to DNA bases, specifically in the strands of DNA that are being transcribed into RNA. The various ways in which Cockayne syndrome could be characterized are discussed.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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New link in a web of human genes
Article Abstract:
It has been possible to identify a functional connection between ATM and NBS1, two genes involved in human diseases. ATM is mutated in the disease ataxia telangiectasia, while NBS1 is mutated in a disease named Nijmegen breakage syndrome.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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In reverse gear
Article Abstract:
Research into Huntington's disease shows that sufferers bear alterations in the HD gene. A new study reveals that when the HD gene is switched on in mice, it is expressed throughout the animal's lifetime.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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