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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences

Article Abstract:

It appears that the evolution of the Campylobacter jejuni genome does not closely reflect that of its small subunit ribosomal RNA. The placement of C. jejuni within the Gram-negative proteobacteria may require a simplified view of the evolutionary origin of its genome. It seems that C. jejuni has a wider repertoire of regulatory systems than Helicobacter pylori, which has a similar sized genome. C. jejuni is unable to use carbohydrates as carbon or energy sources, and this is why very few genes for degradation of carbohydrates or amino acids were found.

Author: Parkhill, J., Wren, B.W., Mungall, K., Ketley, J.M., Churcher, C., Basham, D., Chillingworth, T., Davies, R.M., Feltwell, T., Holroyd, S., Jagels, K., Karlyshev, A.V., Moule, S., Pallen, M.J., Penn, C.W., Quail, M.A., Rajandream, M.-A., Rutherford, K.M., Vliet, A.H.M. van, Whitehead, S., Barrell, B.G.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
Campylobacter

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Complete DNA sequence of a serogroup A strain of Neisseria meningitidis Z2491

Article Abstract:

The complete genome sequence of a serogroup A strain of Neisseria meningitidis Z2491 is reported.

Author: Parkhill, J., Mungall, K., Basham, D., Chillingworth, T., Davies, R.M., Feltwell, T., Holroyd, S., Jagels, K., Moule, S., Quail, M.A., Rutherford, K.M., Whitehead, S., Barrell, B.G., Achtman, M., James, K.D., Bentley, S.D., Chrucher, C., Klee, S.R., Morelli, G., Brown, D., Davis, P., Devlin, K., Hamlin, N., Leather, S., Rajandrea, M.A., Simmonds,M., Skelton, J., Spratt, B.G.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
Neisseria meningitidis

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Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

Article Abstract:

The entire genome sequence of the Mycobacterium tuberculosis, H37Rv strain has been determined and analyzed. A systematic sequence analysis of selected large-insert clones and random small-insert clones was used to obtain the genome sequence, resulting in the sequence of 4,411,529 base pairs. 50 genes coding for functional RNA molecules were discovered, as well as 16 copies of the insertion sequence IS6110 and six of the IS1081 sequence. It shows that the tubercle bacillus is able to synthesize all amino acids, enzyme co-factors and vitamins, differing from other bacteria in that it devotes much of its coding capacity to enzyme production involved in lipogenesis and lipolysis.

Author: Parkhill, J., Churcher, C., Basham, D., Chillingworth, T., Feltwell, T., Holroyd, S., Jagels, K., Moule, S., Quail, M.A., Whitehead, S., Brown, D., Devlin, K., Hamlin, N., Skelton, J., Sulston, J.E., Rogers, J., Taylor, K., Rajandream, M.A., Davies, R., Murphy, L., Brosch, R., Badcock, K., Connor, R., Gentles, S., McLean, J., Cole, S.T., Garnier, T., Harris D., Gordon, S.V., Eiglmeier, K., Gas, s., Barry C.E. III, Takaia, F., Hornsby, T., Krogh, A., OLiver, K., Osborne, J., Rutter, S., Seeger, K., Squares, R., Squares, S., Barrell. B.G.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
Mycobacterium tuberculosis

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Subjects list: Genetic aspects, Research, Genomes
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