The mahogany protein is a receptor involved in suppression of obesity

Article Abstract:

Mutations in the mahogany locus are found to suppress the pleiotropic phenotypes. The mahogany gene and its product has been identified, representing the first positional cloning of a suppressor gene in the mouse. The mahogany locus is found not to suppress the obese phenotype of the melanocortin-4-receptor null allele, but it can suppress diet-induced obesity.

Author: Bork, Peer, Woolf, Elizabeth A., Carlson, George A., Huszar, Dennis, Nagle, Deborah L., Moore, Karen J., Holmgren, Lisa, Baldini, Linda, Ebeling, Chris, Burn, Paul, Fairchild-Huntress, Victoria, McGrail, Sonja H., Vitale, James, Dussault, Barry J. Jr., DiRocco, Lisa, Montagno, Jill, Ge, Pei, Keilty, John, Gilchirst, Julie
Phenotype, Phenotypes

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The missing link with obesity?

Article Abstract:

A new protein, 'resistin' may be involved in molecular mechanisms underlying the link between obesity and diabetes.

Author: Flier, Jeffrey S.

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The hormone resistin links obesity to diabetes

Article Abstract:

The hormone resistin reveals a link between obesity and diabetes.

Author: Steppan, Claire M., Bailey, Shanon T., Bhat, Savitha, Brown, Elizabeth J., Banerjee, Ronadip R., Wright, Christopher M., Patel, Hiralben R., Ahima, Rexford S., Lzer, Mitchell A.
Hormones

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Subjects list: Research, Obesity, Proteins, Diabetes, Diabetes research
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