Abstracts - faqs.org

Abstracts

Zoology and wildlife conservation

Search abstracts:
Abstracts » Zoology and wildlife conservation

Plasma cell differentiation requires the transcription factor XBP-1

Article Abstract:

Research is presented concerning the transcription factors which have been shown to be active in the early stage specification of the B-lymphocyte lineage. The importance of the transcription factor XBP-1 is discussed.

Author: Reimold, Andreas M., Grusby, Michael J., Glimcher, Laurie H., Alt, Frederick, Iwakoshi, Neal N., Manis, John, Vallabhajosyula, Prashanth, Szomolanyi-Tsuda, Eva, Gravallese, Ellen M., Friend, Daniel
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
Cover Story, Physiological aspects, Genetic transcription, Transcription (Genetics), B cells, Immune system

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice

Article Abstract:

Mice that has a germline mutation in activating transcription factor-2 (ATF-2) showed unusual actions of ATF-2 that cannot be found in the other family members of ATF/cAMP response element (CRE). Mutant mice exhibited lower postnatal viability and growth, with defective endochondral ossification at epiphyseal plates similar to human hypochondroplasia. The animals also exhibited hyperactivity, impaired hearing and ataxic gait. ATF-2-deficient mice manifested a need for skeletal and central nervous system development.

Author: Reimold, Andreas M., Grusby, Michael J., Glimcher, Laurie H., Collins, Tucker, Kosaras, Bela, Fries, Jochen W.U., Mori, Ryuji, Maniwa, Sokichi, Clauss, Isabelle M., Sidman, Richard L., Glimcher, Melvin J.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1996
Mice, Mice (Rodents)

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

The transcription factor NF-ATc is essential for cardiac valve formation

Article Abstract:

Nuclear factor of activated T cells (NF-AT) is a group of four linked transcription factors required for cytokine gene expression in activated lymphocytes. Mice with disrupted NF-ATc genes show selective absence of the aortic and pulmonary valves leading to death in utero. However tricuspid and mitral valve morphogenesis is normal. The results suggested that NF-ATc may be essential in signal-transduction needed for normal cardiac valve formation.

Author: Grusby, Michael J., Glimcher, Laurie H., Gravallese, Ellen M., Ranger, Ann M., Mickanin, Craig, Hodge, Martin R., de la Brousse, Fabienne Charles, Hoey, Tim, Scott Baldwin, H.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
Heart valves

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research
Similar abstracts:
  • Abstracts: Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
  • Abstracts: Predator-induced behavior shifts and natural selection in field-experimental lizard populations. Predators increase the risk of catastrophic extinction of prey populations
  • Abstracts: Effect of primary and secondary repellents on European starlings: an initial assessment. Chemical bird repellents: possible use in cyanide ponds
  • Abstracts: Sampling and statistical analysis of snow-urine allantoin-creatinine ratios. Effects of winter road grooming on bison in Yellowstone National Park
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.