A short cut to the nucleus
Article Abstract:
Genetic research indicates that the intracellular biochemical presenilin-1 is directly involved in the Notch intracellular domain (NICD) release mechanism. NICD travels to the nucleus to induce transcription in deoxyribonucleic acid-binding process. Evidence suggests that presenilin-1 is also active in the aging process.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
Research, Genetic regulation, Genetic transcription, Transcription (Genetics), Cellular control mechanisms, Cell regulation
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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JNK is required for effector T-cell function but not for T-cell activation
Article Abstract:
New mouse models with peripheral T cellsHowever, JNK was necessary for T -cell differentiation: there was no production of effector T-cell cytokines in the absence of JNK.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
Cell differentiation, T cells
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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