Trascriptional activation by recruitment
Article Abstract:
Scientific evidence to support the hypothetical gene activation recruitment mechanism indicates that histones actively block the activation site on the deoxyribonucleic acid molecule from holoenzyme activation. Histone depletion results in increased gene expression while high levels of histone are capable of halting transcription. This research suggests histones play a significant role in gene regulation.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
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Ira Herskowitz (1946-2003)
Article Abstract:
OBITUARYIra Herskowitz (1946-2003)Ira Herskowitz got graduation from the Massachusetts Institute of Technology (MIT), and his interest subject was genetics. His famous works include the study of bacteriophage {lambda} and initiated a series of classic studies on the single-celled yeast called Saccharomyces cerevisiae.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
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Telomere looping permits gene activation by a downstream UAS in yeast
Article Abstract:
A new study investigates telomere looping in yeast and its role in gene activation.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2001
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