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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer

Article Abstract:

An identification of LIV1, abreast-cancer -associated zinc transporter protein, as a downstream target of STAT3 that is essential and sufficient for STAT3's cell-autonomous role in the epithelial-mesenchymal transition (EMT) of zebrafish gastrula organizer cells is presented. The essentiality of the LIV1 for the nuclear localization of zinc-finger protein Snail, a master regulator of EMT is demonstrated.

Author: Yamashita, Susumu, Miyagi, Chiemi, Fukada, Toshiyuki, Kagara, Naofumi, Yong-Suk Che, Hirano, Toshio
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Health aspects, Zebra fish, Zebra fishes

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Time for a medical

Article Abstract:

The resignation of Pfizer's chief financial officer and concerns on the safety of GlaxoSmithKline's diabetes drug Avandia have created great tension for the pharmaceutical industry in the U.S. This has come at an unfortunate time when the industry is still coming to terms with the problems with regulation and business.

Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
Political aspects, Pharmaceutical laws

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Keeping faith with trial volunteers

Article Abstract:

The equal partnership between the funding pharmaceutical company academic investigators in clinical trials ensure that interests of patients participating in the trials are not compromised.

Author: Goldhirsch, Aron, Piccart, Martine
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
Product development, Clinical trials

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Subjects list: Care and treatment, Research, Breast cancer, United States, Management, Pharmaceutical industry, Company business management
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