p19(super ARF) directly and differentially controls the functions of c-Myc independently of p53

Article Abstract:

ARF can inhibit c-Myc by a unique and direct mechanism that is independent of p53. It is observed that when c-Myc increases, ARF binds with c-Myc and dramatically blocks c-Myc's ability to activate transcription and induce hyperproliferation and transformation.

Author: Ying Qi; Hann, Stephen R., Gregory, Mark A., Zhaoliang Li, Brousal, Jeffrey P., West, Kimberly
Genetic transcription, Transcription (Genetics), Apoptosis

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Mentors and manipulation

Article Abstract:

A young researcher relates how two Nobel laureates helped him to test an idea regarding cells and their antibodies. He recollects the techniques used for the research.

Author: Nossal, G.J.V.
Social aspects, Personal narratives, Nobel laureates

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Mentors of tomorrow

Article Abstract:

The guidelines to elements of good peer review for aspects of mentoring to follow ethical practice and do justice while assessing other researchers work is presented.

Ethics, Evaluation, Ethical aspects, Peer counseling, Research ethics, Peer counselling

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Subjects list: Research, United States, Viral antibodies, Antibodies, Research scientists
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