A C. elegans sperm TRP protein required for sperm-egg interactions during fertilization

Article Abstract:

Results demonstrate that the transient receptor potential-3 (TRP-3), a sperm-enriched C. elegans TRP-canonical, translocates to the plasma membrane during sperm activation and mediates sperm-egg fertilization. Mutants defective for trp-3 gene are unable to fertilize oocytes following gamete contact. Furthermore, TRPC channels may mediate calcium flux required for sperm-egg-plasma membrane interactions.

Genetic regulation, Cell receptors, Ion channels, Spermatozoa, Sperm, Fertilization (Biology)

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Working in the post-genomic C. elegans world

Article Abstract:

The author reviews the publications on the Caenorhabditis elegans genomic sequence. The topics of interest include comparative worm genetics, the cloning of the gene defined by mutation and functional genomics.

Gene mutations, Gene mutation, Genetic aspects, Cloning

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Regulation of distinct muscle behaviors controls the C. elegans male's copulatory spicules during mating

Article Abstract:

Research has been conducted on the Caenorhabditis elegans male mating behavior. The molecular, pharmacological and cell ablation approaches have been used in investigating spicule insertion at multiple levels.

Neurons, Muscle cells

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