A DNA integrity network in the yeast Saccharomyces cerevisiae
Article Abstract:
A network governing DNA integrity was identified in yeast by a global genetic analysis of synthetic fitness or lethality defect (SFL) interactions. Modules or genes involved in DNA replication, DNA replication, DNA-replication checkpoint (DRC) signaling, and oxidative stress response were identified as the major guardians against lethal spontaneous DNA damage, efficient repair of which requires the function of the DNA-damage checkpoint signaling and multiple DNA-repair pathways.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast.
Article Abstract:
The FLO gene family of saccharomyces cerevisiae includes an expressed gene, FLO11 and a set of silent, telomere-adjacent FLO genes. Genetic and epigenetic variations explain the observed heterogeneity of cell-surface protein expression within a population of cells derived from a single clone.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
Global analysis of protein palmitoylation in yeast
Article Abstract:
A new proteomic methodology is used that purifies and identifies palmitoylated proteins to characterize the palmitoyl proteome of the yeast Saccharomyces cerevisiae. This approach identifies 12 of the 15 known palmitoyl proteins plus many new palmitoyl proteins.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Two distinct pathways for trehalose assimilation in the yeast saccharomyces cerevisiae. Saccharomyces cerevisiae JEN1 promoter activity is inversely related to concentration of repressing sugar
- Abstracts: The central Siberian origin for Native American Y chromosomes. Genetic variation at the ApoB 3' HVR minisatellite locus in Mbenzele Pygmies from the Central African Republic
- Abstracts: Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing. The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae
- Abstracts: Maintenance of clonal diversity in Dipsa bifurcata (Fallen, 1810) (Diptera: Lonchopteridae). Genetic diversity and differentiation in Eryngium alpinum L. (apiaceae): comparison of AFLP and microsatellite markers
- Abstracts: Neuroblast formation and patterning during early brain development in Drosophila. New tool for an old problem: Can RNAi efficiently resolve the issue of genetic redundancy?