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A novel checkpoint mechanism regulating the G1/S transition

Article Abstract:

The mechanism of cell cycle delay in the G1 phase of chromatic binding in yeast cells in the S-phase entry is investigated. It was observed that the cell cycle delay functions as a novel checkpoint using a novel mechanism involving the Gen2 kinase, which regulates translation according to the nutrient supply.

Author: Kearsey, Stephen E., Boye, Erik, Jvegard, Tonje, Soltani, Hela, Grallert, Beata, Skjolberg, Henriette C., Krohn, Marit, Nilssen, Esben A.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
United Kingdom, Analysis, Physiological aspects, Ultraviolet radiation, Cell cycle, Protein binding

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Budding yeast Hed1 down-regulates the mitotic recombination machinery when meiotic recombination is impaired

Article Abstract:

A meiosis-specific protein (Hed1) with a novel Rad51 regulatory function is described. It is proposed that Hed1 protein provides a mechanism to ensure the coordinated action of Rad51 and Dmc1 during meiosis, by down-regulating Rad51 activity when Dmc1 is unavailable.

Author: Roeder, G. Shirleen, Tsubouchi, Hideo
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2006
Genetic aspects, Genetic research, Meiosis, Budding, Budding (Reproduction)

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Subjects list: Research, Yeast fungi, Yeasts (Fungi)
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