Autosomal dominant orthostatic hypotensive disorder maps to chromosome 18q

Article Abstract:

Mapping of autosomal dominant orthostatic hypotensive disorder to chromosome 18q is discussed with information about three families and a genomewide scan in the two largest ones. General regulatory pathways in the range of blood pressures that exist may be better understood if the gene responsible for orthostatic hypotensive disorder in the families is identified.

United States, Statistical Data Included, Usage, Chromosome mapping, Genetic disorders, Hypotension, Orthostatic, Orthostatic hypotension

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A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population

Article Abstract:

A genomewide screen of the families with late-onset Alzheimer's disease (AD) is a genetically isolated community from the southwestern area of The Netherlands is presented. This genomewide screen has displayed significant linkage to chromosome 3q23 markers and the analysis has confirmed linkage to chromosome 11q25.

Netherlands, Genetic research, Dutch, Dutch (European people)

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Association of polymorphisms in the angiotensin-converting enzyme gene with Alzheimer disease in an Israeli Arab community

Article Abstract:

A study to understand the association of polymorphisms in the angiotensin-converting enzyme gene with Alzheimer disease (AD) in an Israeli Arab community is presented. The results suggest that a variant in close proximity to rs4343 and rs4351 modulates susceptibility to AD in this community.

Ohio, Health aspects, Genetic polymorphisms, Israelis

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