Keystone meeting summery: 'Adipogenesis, obesity, and inflation' and 'diabetes mellitus and the control of cellular energy metabolism,' January 21-26, 2006, Vancouver, Canada

Article Abstract:

Nine hundred scientists from around the world gathered at the January 21-26, 2006 gathering in Vancouver, to exchange insights into the cellular deficiencies leading to the inability to properly store and use excess energy, and ultimately to insulin resistance and beta-cell failure. Molecular consequences of obesity in terms of promoting risk for type 2 diabetes and cardiovascular disease were also highlighted.

Complications and side effects, Risk factors, Genetic aspects, Obesity, Type 2 diabetes, Energy metabolism, Bioenergetics, Metabolic diseases

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Critical and distinct roles for key RET tyrosine docking sites in renal development

Article Abstract:

The wild type human RET9 or RET51 cDNA were targeted to study the role of RET isoforms and their key docking tyrosines (Y981, Y1015, Y1062) in kidney development. The results suggest that a wide spectrum of congenital anomalies due to UB outgrowth in humans could be due to alterations in levels of the RET-dependent AKT/MAPK pathway.

Tyrosine, Cell physiology

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