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Complex segregation analysis of canine hip dysplasia in German shepherd dogs

Article Abstract:

The mode of inheritance of canine hip dysplasia (CHD) in German shepherd dogs were analyzed and clarified through complex segregation. Although only small frequencies were found for the unfavorable homozygotic genotype AA, the probability of the AB genotype was high in affected animals.

Author: Hamann, H., Distl, O., Janutta, V.
Publisher: Oxford University Press
Publication Name: The Journal of Heredity
Subject: Biological sciences
ISSN: 0022-1503
Year: 2006
Germany, Health aspects, Analysis, Dysplasia, Dog breeding, Quantitative trait loci

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Exclusion of Urate Oxidase as a Candidate Gene for Hyperuricosuria in the Dalmatian Dog Using an Interbreed Backcross

Article Abstract:

Segregation involving the microsatellite markers surrounding the locus for urate oxidase was tracked, and findings show that the uox gene can be excluded for hyperuricosuria in Dalmatians based on negative LOD scores and the cDNA sequence identity.

Author: Bannasch, D.L., Safra, N., Ling, G.V., Schaible, R.H.
Publisher: Oxford University Press
Publication Name: The Journal of Heredity
Subject: Biological sciences
ISSN: 0022-1503
Year: 2005
Diseases, Comparative analysis, Genetic markers, Urologic diseases, Dog diseases, Dalmatians, Dalmatians (Dogs)

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Subjects list: Research, Genetic aspects, Dogs
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