DNA deamination mediates innate immunity to retroviral infection

Article Abstract:

Research indicates that built-in immunity to retroviruses results from DNA deamination as shown by the incorporation of DNA deaminase into virions during viral development triggering viral destruction. Data show that the enzyme is involved in a massive deamination of deoxycytidine to deoxyuridine within the retroviral cDNA strand.

United Kingdom, Biological Product (except Diagnostic) Manufacturing, Drugs, Deoxyribonucleic Acid, Physiological aspects, Influence, HIV infection, HIV infections, DNA, Heterocyclic compounds, Retroviruses

---

Extracellular crosstalk: when GDNF meets N-CAM

Article Abstract:

The authors discuss the study on a receptor for glial cell line-derived neurotrophic factor. The topics of interest include RET-dependent glial cell line-derived neurotrophic factor signaling and the role of glial cell line-derived neurotrophic factor-neural cell adhesion molecule pathway.

United States, Genetic aspects, Growth, Axons, Neurons, Neuroglia, Glia, Cell adhesion, Cell migration, Cell research, Cytological research, Schwann cells, Company growth, Neurotrophins, Glial cell line-derived neurotrophic factor

---

Similar abstracts:

• Abstracts: Characterization of cry genes in a Mexican Bacillus thuringiensis strain collection. Identification of a putative Mexican strain of Serratia entomophila pathogenic against root-damaging larvae of scarabaeidae (Coleoptera)
• Abstracts: Identification of cryptic rearrangements in patients with 18q- deletion syndrome. Evidence for a novel osteosarcoma tumor-suppressor gene in the chromosome 18 region genetically linked with Paget disease of bone
• Abstracts: Why do females mate multiply? A review of the genetic benefits. Seeing in the dark: molecular approaches to the study of bat populations
• Abstracts: A signal transduction system that responds to extracellular iron. A mechanism for coupling exit from mitosis to partitioning of the nucleus
• Abstracts: Study of the response of a biofilm bacterial community to UV radiation. Genetic diversity among Arthrobacter species collected across a heterogeneous series of terrestrial deep-subsurface sediments as determined on the basis of 16S rRNA and recA gene sequences

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.