Developmental regulation of SR protein phosphorylation and activity

Article Abstract:

Developmental regulation of splicing factor (SR protein) activity and phosphorylation has been explored. It seems changes in SR protein phosphorylation play a role in activation of pre-mRNA splicing in early development. These serine/arginine-rich proteins are substrates for serine phosphorylation and can regulate SR protein function. Gross changes in SR protein phosphorylation have been seen in early development along with major zygotic gene activation in Ascaris lumbricoides, a nematode. The differences correlate with major changes in SR protein activity in promoting cis-and trans-splicing. Early stage extracts can be made splicing-competent by addition of later stage SR proteins.

United States, Genetic aspects, Phosphorylation, RNA splicing, Genetic research, Ascaris

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Temporal and spatial regulation of Rho-type guanine-nucleotide exchange factors: the yeast perspective

Article Abstract:

Cell developmental processes involving cytoskeletal rearrangements are regulated by guanine triphosphatases (GTPases) of the Rho and Ras subfamilies, which in turn have to be activated by several growth factors. This review focuses on the spatial and temporal regulation of guanine-nucleotide exchange factors that regulate Rho-type GTPases.

Cell differentiation, G proteins, Cytoskeletal proteins

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INNER NO OUTER regulates abaxial-adaxial patterning in Arabidopsis ovules

Article Abstract:

Results show that INNER NO OUTER (INO) gene is a positive regulator of its own expression and the spatial pattern of INO expression is brought about co-operatively in combination with other regulatory genes.

Statistical Data Included, Analysis, Genetic transcription, Transcription (Genetics), Developmental genetics, Arabidopsis

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