Distinct behavioral responses to ethanol are regulated by alternate RhoGAP18B isoforms

Article Abstract:

The characterization of mutations in the Drosophila RhoGAP18B gene, isolated due to their strong resistance to the sedating effects of ethanol is described. The data from result demonstrate that Rho-type GTPases are intimately involved in the regulation of behavioral responses to ethanol exposure, implicating actin dynamics in the process.

Industrial organic chemicals, not elsewhere classified, Ethanol, Ethyl Alcohol Manufacturing, Alcohol, Alcohol, Denatured, Guanosine triphosphatase, GTPases

---

Flies without centrioles

Article Abstract:

The mutation in the Drosophila DSas-4 gene is analyzed and shown that it is essential for centriole replication. The results have shown that centrioles are essential for the formation of centrosomes, cilia and flagella, but are not essential for most aspects of Drosophila development.

Centrioles

---

The v-ATPase Vo subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila

Article Abstract:

Loss-of-function mutations in vha100-1 that indicate a defect late in synaptic vesicle exocytosis are reported. It is observed that Vha 100-1 is a regulator of synaptic vesicle fusion efficiency downstream of soluble NSF-attachment protein receptors (SNARE)-dependent vesicle priming.

Exocytosis

Similar abstracts:

• Abstracts: Structural insights into RNA-dependent ring closure and ATPase activation by the Rho termination factor. Activation of glucosidase via stress-induced polymerization rapidly increases active pools of abscisic acid
• Abstracts: A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced
• Abstracts: Identification of bacteria potentially responsible for oxic and anoxic sulfide oxidation in biofilters of a recirculating mariculture system
• Abstracts: Influence of environmental conditions on methanogenic compositions in anerobic biogas reactors. Methanosarcina spp. drive vinyl chloride dechlorination via interspecies hydrogen transfer
• Abstracts: Peroxisomal bifunctional protein deficiency revisited: resolution of its true enzymatic and molecular basis. Mutations in the gene encoding peroxisomal sterol carrier protein X (SCPx) cause leukencephalopathy with dystonia and motor neuropathy

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.