Regulation of body pigmentation by the Abdominal-B Hox protein and its gain and loss in Drosophila evolution

Article Abstract:

The Abdominal-B (ABD-B) Hox protein is shown to directly activate the expression of the yellow pigmentation gene in the male A5 and A6 segments through binding sites in a specific cis-regulatory element (CRE) of the yellow gene. The results have demonstrated that Hox proteins directly activate terminal phenotypes and that the gain and loss of Hox regulation occur at the level of individual species through modifications of CREs.

Physiological aspects, Drosophila, Skin color, Skin colour

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Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity

Article Abstract:

An extensive experimental/computational study of an HIV-1 model vector is presented. It shows that stochastic fluctuations in Tat influence the viral latency decision.

Biological diversity, Biodiversity, Gene expression, Phenotype, Phenotypes

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