High-level acetaldehyde production in Lactococcus lactis by metabolic engineering

Article Abstract:

The efficient rerouting of pyruvate towards acetaldehyde in Lactococcus lactis by functional expression of pyruvate decarboxylase, originating from the gram-negative eth-anologenic bacterium Zymomonas mobilis is described. In resting cells, almost 50% of the glucose consumed could be redirected towards acetaldehyde by combined overexpression of pdc and nox under anaerrobic conditions.

All Other Basic Organic Chemical Manufacturing, Industrial organic chemicals, not elsewhere classified, Acetaldehyde

---

Production of dehydroamino acid-containing peptides by Lactococcus lactics

Article Abstract:

Nisin, a pentacyclic peptide antibiotic, contains dehydroresidues and thioether rings that are introduced by membrane-associated enzyme complex composed of a serine and threonine dehydratase NisB and the cyclase NisC. The potential of lactococcus lactics expressing NisB and NisC are studied to produce peptitides whose serines and threonines are dehydrated.

Antibiotics, Structure, Chemical properties, Report, Dehydrocholic acid

---

Gene targeting in the gram-positive bacterium Lactococcus lactis, using various delta ribozymes

Article Abstract:

A study was conducted on the use of two variants of the trans-acting anti-genomic delta ribozyme targeting the abundant EF-Tu mRNA in the industrially important gram-positive bacterium Lactococcus lactis. The results showed the high stability in vivo, of the two variants, when expressed at significant levels.

Analysis, Usage, Nucleic acids, Catalytic RNA, Computational biology, Nucleic acid isolation

Similar abstracts:

• Abstracts: The pool of ADP and ATP regulates anaerobic product formation in resting cells of Lactococcus lactis. Reappraisal of the regulation of lactococcal L-lactate dehydrogenase
• Abstracts: Conversion of Sphingobium chlorophenolicum ATCC 39723 to a hexachlorobenzene degrader by metabolic engineering
• Abstracts: Increased carotenoid production by the food yeast Candida utilis through metabolic engineering of the isoprenoid pathway
• Abstracts: Several archael homologs of putative oligopeptide-binding proteins encoded by Thermotoga maritima bind sugars
• Abstracts: Monitoring methanotrophic bacteria in hybrid anaerobic-aerobic reactors with PCR and a catabolic gene probe. Multicopy integration and expression of heterologous genes in Methylobacterium extorquens ATCC 55366

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.