Hox transcription factors and their elusive mammalian gene targets

Article Abstract:

The pathways involved in developmental and normal cellular processes are regulated by the Hox family of homeodomain transcription factors. A review is presented of the transcriptional and functional specificity brought out by Hox proteins with an overview of homeodomain-DNA interactions and the gain of binding specificity through cooperative binding with cofactors.

Science & research, Research, Homeobox genes, Genetic research

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New saliva DNA collection method compared to buccal cell collection techniques for epidemiological studies

Article Abstract:

The DNA yield and quality from a novel whole-saliva collection device were compared with noninvasive methods such as cytobrush, foam swab and oral rinse tested on a sample of 17 adults. The quality and quantity of DNA obtained using whole saliva and oral-rinse methods were found to be superior to that of the cytobrush and foam swab methods.

Analysis, Salivary glands, Saliva

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