Influence of carbohydrate starvation and arginine on culturability and amino acid utilization of Lactococcus lactis subsp. lactis

Article Abstract:

Research was conducted to examine the role of lactose and arginine on the amino acid metabolism and culturability of Lactococcus lactis. The objective was to determine if L. lactis could become VBNC after the exhaustion of lactose when arginine and other amino acids are present. Results suggest that lactococci maintains its viability even in the absence of arginine or lactose.

Research, Microbial metabolism, Arginine, Amino acids, Lactose

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Identification of the leucine-to-2-methylbutiric acid catabolic pathway of Lactococcus lactis

Article Abstract:

Lactococcus lactis IL1403 consumed leucine to produce 2-methylbutyric acid, alpha-ketoisocaproate, alpha-ketoisovalerate, HMGA, glutamate and citrate during carbohydrate starvation and NC. Gene expression profiles coupled with intermediate metabolite analysis and in silico analysis resulted in identification of a catabolic pathway previously uncharacterized in firmcutes.

Leucine, Chemical properties, Catabolism

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Carbohydrate starvation causes a metabolically active but nonculturable state in Lactococcus lactis

Article Abstract:

The ability of lactococci to become nonculturable under carbohydrate starvation while maintaining metabolic activity in Lactococcus lactis is characterized. The analysis has shown that carbohydrate-starved lactococci can attain a nonculturable state wherein sugar metabolism, cell division and autolysis are inhibited.

Pharmaceutical Preparation Manufacturing, Pharmaceutical preparations, Carbohydrates, Health aspects, Physiological aspects, Cell division

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